The 15 best acid reducer brands

  • 15 brands ranked
  • Ranked by brand visibility

PEPCID, Kirkland Signature and Prilosec OTC lead our ranking of 15 acid reducer brands. Compare what each brand makes, visit its official site, or shop it online.

Acid Reducer brands, ranked

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  1. 1

    PEPCID

    Famotidine tablets that work as an H2 blocker, reducing the acid your stomach produces rather than neutralizing what is already there.

    Top products: Pepcid AC Maximum Strength· Pepcid AC Original Strength

    Popularity 10.0/10

  2. 2

    Kirkland Signature

    Costco's private label, sold in large counts of omeprazole and famotidine tablets, usually cheaper per dose than name-brand reducers.

    Top products: Acid Controller· Omeprazole 20 mg 24HR

    Popularity 6.3/10

  3. 3

    Prilosec OTC

    Original 20 mg proton pump tablets taken once daily before a meal, used in 14-day courses for frequent heartburn.

    Top products: Prilosec OTC

    Popularity 6.2/10

  4. 4

    Tagamet

    Cimetidine, an older H2 blocker sold as HB 200 mg tablets, including a cool mint version for quick use after eating.

    Top products: Tagamet HB 200mg

    Popularity 3.6/10

  5. 5

    GoodSense

    Store-label omeprazole and famotidine acid reducers sold in multipacks, including orally disintegrating omeprazole tablets for easy swallowing.

    Top products: GoodSense Omeprazole Delayed Release· GoodSense Famotidine 10mg

    Popularity 3.5/10

  6. 6

    TUMS

    Calcium carbonate antacid chews and tablets that neutralize stomach acid quickly, with flavours and smoothie-style options.

    Popularity 2.8/10

  7. 7

    Alka-Seltzer

    The original formula contains aspirin, so skip it if you cannot take NSAID pain relievers.

    Popularity 2.2/10

  8. 8

    Rolaids

    Pairs calcium carbonate with magnesium hydroxide, so the mix balances the constipating effect of calcium alone.

    Popularity 2.2/10

  9. 9

    Zegerid

    Sodium bicarbonate buffers the omeprazole in these capsules and packets, which is meant to speed up relief compared with plain tablets.

    Popularity 1.8/10

  10. 10

    Eno

    Contains sodium bicarbonate and citric acid, so people on low-sodium diets should check with a doctor first.

    Popularity 1.5/10

  11. 11

    Perrigo

    Contract and store-brand OTC maker, so many of its acid reducers sell under retailer labels, typically famotidine or omeprazole tablets.

    Popularity 0.9/10

  12. 12

    Assured

    Assured Allies is a caregiving company that assists families with aging issues. They offer various services, ranging from basic in-home care to dementia and Alzheimer's care. They recognize how difficult it may be for family caregivers to juggle their responsibilities...

    Popularity 0.9/10

  13. 13

    Johnson & Johnson

    Doc Johnson has celebrated over 45 years as the leading player in the adult novelty industry. Rather than spreading its wings and flying abroad, the brand has decided to grow its even roots further and stick to its Californian heritage....

    Popularity 0.7/10

  14. 14

    Gaviscon

    Alginate-based liquid and chewable tablets that form a protective layer floating on stomach contents to block reflux.

    Popularity 0.7/10

  15. 15

    Phazyme

    Simethicone tablets and softgels that break up gas bubbles, aimed at bloating rather than acid.

    Popularity 0.7/10